GLP-3 (Pen)

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Metabolic Research Pens

GLP-3 (Pen)

47 reviews

Price range: $159.99 through $237.99

GLP-3 (retatrutide) pen — retatrutide (LY3437943) in a pre-filled research format, 10mg or 20mg fill, for laboratory research only. Synthetic triple GIP/GLP-1/glucagon receptor agonist; investigational, unapproved. Janoshik report #232263 (99.079%) is filed for the 10mg pen; no report is posted for the 20mg pen. CAD pricing, shipped within Canada by Canada Post. Not for human or animal use.

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Customer Reviews

4.94 out of 5
Based on 47 reviews
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  1. Jenna Gray (verified owner) –

    the reta page helped a lot. I always check COA info and labeling before I buy.

  2. Josh Barnes (verified owner) –

    retatrutide 10mg was easy to find on the site. the label matched the item I picked, which I always check first. worked out well.

  3. Blake Wood (verified owner) –

    the reta page helped a lot. I always check COA info & labeling before I buy.

  4. Spencer Lewis (verified owner) –

    grabbed Retatrutide 10mg after comparing a few listings. everything was packed tight and looked professional. worked out well.

  5. Emily Roberts (verified owner) –

    came back for Retatrutide 20mg because the product page was clear. the page felt clean, especially the COA section. site feels much easier than a lot of peptide shops.

  6. Spencer King (verified owner) –

    got Retatrutide 20mg without any back and forth. pretty smooth.

  7. Emily Gonzales (verified owner) –

    i liked the docs layout on Retatrutide 20mg. shipping was normal and clean.

  8. Jessica Garcia (verified owner) –

    Retatrutide 10mg was easy to find on the site. checkout didnt fight me and the summary looked right. pretty straightforward.

  9. Lucas Turner (verified owner) –

    came back for Retatrutide 20mg because the product page was clear. support answered a small question before I ordered. site feels much easier than a lot of peptide shops.

  10. Casey Nelson (verified owner) –

    not much to complain about with Retatrutide 10mg. packaging was neat and nothing was leaking or loose. good first impression.

  11. Tyler Young (verified owner) –

    i liked how Retatrutide 20mg was laid out on the page. received exactly what was on the order page. good first impression.

  12. Cameron Clark (verified owner) –

    quick order for Retatrutide 10mg, simple checkout. the checkout email and tracking lined up fine. good enough for a reorder.

  13. Courtney Nelson (verified owner) –

    got Retatrutide 10mg without any back and forth. pretty smooth.

  14. Amanda Stewart (verified owner) –

    the Retatrutide page helped a lot. I always check COA info and labeling before I buy.

  15. Laura Sanchez (verified owner) –

    i liked how Retatrutide 10mg was laid out on the page. COA info was easy to spot before checkout. better than expected.

  16. Megan Gray (verified owner) –

    Retatrutide 20mg came in fine. checkout was quick and tracking was easy to follow.

  17. Ian Edwards (verified owner) –

    simple order. Retatrutide 20mg page had the info I needed.

  18. Austin White (verified owner) –

    grabbed Retatrutide 20mg after comparing a few listings. received exactly what was on the order page. worked out well.

  19. Austin Anderson (verified owner) –

    ordered Retatrutide 10mg & the whole thing was pretty smooth. everything was packed tight and looked professional. would order again.

  20. Kevin Hill (verified owner) –

    the Retatrutide page made it easy to verify what I was ordering. no surprises at checkout.

  21. Ashley Green (verified owner) –

    not much to complain about with Retatrutide 20mg. support answered a small question before I ordered. overall happy with it.

  22. Alicia Evans (verified owner) –

    the Retatrutide 10mg listing answered most of my questions. I liked that the research-only language stayed visible. pretty straightforward.

  23. Caleb Cook (verified owner) –

    liked the size options. package l&ed in good shape and the email updates were on time.

  24. Laura Richardson (verified owner) –

    no weird checkout issues. Retatrutide 10mg showed up as listed.

  25. Nathan Roberts (verified owner) –

    ordered Retatrutide 20mg and the whole thing was pretty smooth. support answered a small question before I ordered. thats all I needed.

  26. Megan Hall (verified owner) –

    mobile checkout worked fine for Retatrutide 10mg. that matters to me.

  27. Garrett King (verified owner) –

    came back for Retatrutide 10mg because the product page was clear. everything was packed tight and looked professional. nice and simple.

  28. Logan Reed (verified owner) –

    good packaging on Retatrutide 20mg. label & size matched the order.

  29. Grace Price (verified owner) –

    i liked how Retatrutide 20mg was laid out on the page. the batch documentation was easier to read than most sites. overall happy with it.

  30. Kyle Jenkins (verified owner) –

    good packaging on Retatrutide 20mg. label and size matched the order.

  31. Carla Price (verified owner) –

    first time ordering Retatrutide 20mg from this shop. packaging was neat and nothing was leaking or loose. clean experience.

  32. Garrett Ross (verified owner) –

    Retatrutide 20mg was easy to find on the site. the label matched the item I picked, which I always check first. overall happy with it.

  33. Jordan Hayes (verified owner) –

    reta page looked clean on desktop and mobile. shipping was quick enough for me.

  34. Logan Anderson (verified owner) –

    the Retatrutide 10mg listing answered most of my questions. checkout didnt fight me and the summary looked right. good enough for a reorder.

  35. Erica Hughes (verified owner) –

    grabbed Retatrutide 10mg after comparing a few listings. the product card made it easy to compare sizes. would order again.

  36. Michael Baker (verified owner) –

    Retatrutide 20mg was easy to find on the site. COA info was easy to spot before checkout. no issues from my side.

  37. Sean Sanchez (verified owner) –

    not fancy, just clear. Retatrutide 10mg arrived packed well.

  38. Megan Davis (verified owner) –

    grabbed Retatrutide 20mg after comparing a few listings. checkout didnt fight me and the summary looked right. pretty straightforward.

  39. Cody Edwards (verified owner) –

    placed a small order for Retatrutide 10mg and had no drama. delivery was faster than I expected for a first order. clean experience.

  40. Diana Cox (verified owner) –

    placed a small order for Retatrutide 20mg & had no drama. support answered a small question before I ordered. clean experience.

  41. Tina Johnson (verified owner) –

    solid experience buying Retatrutide 20mg. the batch documentation was easier to read than most sites. would order again.

  42. Abigail Morris (verified owner) –

    Retatrutide 20mg was easy to find on the site. shipping updates were clear, no guessing game. pretty straightforward.

  43. Melissa Green (verified owner) –

    no weird checkout issues. Retatrutide 20mg showed up as listed.

  44. Katelyn Davis (verified owner) –

    fast ship, clean box, and the COA was easy to find for Retatrutide 20mg.

  45. Daniel Carter (verified owner) –

    quick order for Retatrutide 10mg, simple checkout. the product card made it easy to compare sizes. good first impression.

  46. Jake Hall (verified owner) –

    Reta listing looked clean on desktop and mobile. shipping was quick enough for me.

  47. Alicia Garcia (verified owner) –

    retatrutide 20mg was listed clearly and the cart summary matched.

Description

GLP-3 (retatrutide) pen — research format, Canada

Researched & reviewed by the SPO Quality Team · Last reviewed: 30 September 2026

The pen listing carries the same peptide as the GLP-3 vials — retatrutide, LY3437943, a 39-residue synthetic molecule with agonist activity at the GIP, GLP-1 and glucagon receptors[1] — in a pre-filled research format offered in two fills, 10mg and 20mg. Retatrutide is an investigational drug with published phase 2 and phase 3 trials and no marketing approval anywhere[3, 4]. The pen is a laboratory convenience for repeatable, logged handling; it is not a medical device and not the clinical product.

Full research overview, study table & references → GLP-3 (retatrutide) in Canada: research guide

Identity at a glance

Compound Retatrutide (INN); LY3437943; catalogue name “GLP-3 (RT)”
Structure 39-residue single-chain peptide with a C20 fatty-diacid side chain at Lys17 and Aib at positions 2 and 20; C-terminal amide (FDA GSRS)
Formula / MW C221H342N46O68 / 4731 g/mol (PubChem CID 171390338)
CAS 2381089-83-2
Receptors studied GIP, GLP-1 and glucagon receptors — one molecule, three targets[1]
Status Investigational (Eli Lilly); not approved anywhere[7]

This batch: certificate of analysis (10mg pen only)

Library entry “Retatrutide 10 mg (Pen)” — the COA library assigns this report to the 10mg pen variation of this listing; per the supplier, the 10mg pen is filled from the same batch as the 10mg vial
Testing laboratory Janoshik Analytical (independent)
Report number #232263
Sample received / analysed 16 September 2026 / 21 September 2026
Test Common GLP-1 peptide blind test (Semaglutide, Tirzepatide and Retatrutide); sample identified as retatrutide
Measured content 9.24 mg (labelled 10 mg)
Purity (HPLC) 99.079%
Verification key LBUI98X8TRUG (checkable at janoshik.com)
Report View the report image · COA library
Janoshik test report #232263 for Retatrutide 10 mg: content 9.24 mg, purity 99.079%, analysed 21 September 2026
Independent test report #232263 (Janoshik, 21 September 2026) as filed in the COA library under “Retatrutide 10 mg (Pen)”: content 9.24 mg, purity 99.079%.

Read this carefully. The report describes a 10 mg retatrutide batch. Per the supplier, the 10mg pen is filled from the same batch as the 10mg vial, which is why the COA library files this report under both. Match the lot on your pen’s label to the report before relying on it. The 20mg pen has no posted report — a batch-specific COA for that strength has not been posted yet; see the COA library (/coa/).

What researchers have looked at

  • Origin (2022): designed at Eli Lilly as a single peptide with balanced glucagon- and GLP-1-receptor activity and stronger GIP-receptor activity; in obese mice it lowered weight and improved glycaemic control[1].
  • First multiple-dose human data (2022): a 12-week phase 1b trial in 72 adults with type 2 diabetes had safety and tolerability as its primary outcome; gastrointestinal disorders led the adverse events and 29 participants discontinued early[2].
  • Phase 2 and 3 (2023–2026): dose-dependent weight reductions versus placebo, with dose-related gastrointestinal events and heart-rate increases in the 48-week phase 2 trial[3] and an 80-week phase 3 trial of 1,152 adults with obesity and type 2 diabetes[4].
  • Grey-market products (2026): an Australian study analysed what products sold as “retatrutide” actually contained and how accurately they were labelled[5]; a case report describes impending ketoacidosis in a man with type 1 diabetes after an online-sourced product[6].

Those are results for a pharmaceutical-grade investigational drug in registered trials, or for products that are not this one. They are not claims about this pen.

Storage and handling

  • Store the pen as its label directs; the site’s general guidance for lyophilized retatrutide is −20 °C for long-term storage (stated stability up to 24 months) and cool, dry, dark conditions for short holds, without repeated freeze–thaw.
  • Log the fill (10mg or 20mg), the lot and the dates received and opened, and match the lot to its report. Handling protocols are the researcher’s responsibility and are not described on this site.

Vial formats: GLP-3 (RT) 5MG · GLP-3 (RT) 10MG (posted COA) · GLP-3 (RT) 20MG · GLP-3 60MG. Shipping is from inside Canada by Canada Post; the shipping policy lists cut-off, delivery times and the free-shipping threshold. Everything we carry is on the page where you can buy peptides online in Canada.

Related reading: Peptide pen vs vial: formats compared

Frequently asked questions

Can I buy the GLP-3 (retatrutide) pen in Canada?

Yes. Shop Peptides Online supplies the retatrutide pen in 10mg and 20mg fills as research-grade material and ships it from inside Canada by Canada Post. Laboratory research only; retatrutide is an investigational, unapproved compound (PMID 41785010).

Is there a COA for the GLP-3 pen?

For the 10mg pen, the COA library files Janoshik report #232263 (sample received 16 September 2026, analysed 21 September 2026): 9.24 mg measured against a 10 mg label, purity 99.079%, verification key LBUI98X8TRUG. Per the supplier, the 10mg pen is filled from the same batch as the 10mg vial, so this report covers both. No report is posted for the 20mg pen.

What is the difference between the pen and the vials?

The peptide is the same retatrutide; the pen is a pre-filled research format for laboratories that want repeatable, logged handling, and it is offered in two fills. Vials of 5mg, 10mg, 20mg and 60mg are listed separately. Choose by the format your inventory system records, not by any assumption about content — only a batch report gives a measured amount.

Is the GLP-3 pen for human use?

No. It is research-grade material for laboratory use only, not for human or animal consumption. Retatrutide is not approved by Health Canada, the FDA or the EMA; a 2026 case report describes a hospital admission after an online-purchased product (PMID 42669023); and Shop Peptides Online provides no dosing or administration guidance.

References

  1. Coskun T, Urva S et al. (2022). LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept. Cell Metab. PMID 35985340
  2. Urva S, Coskun T et al. (2022). LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial. Lancet. PMID 36354040
  3. Jastreboff AM, Kaplan LM et al. (2023). Triple-Hormone-Receptor Agonist Retatrutide for Obesity – A Phase 2 Trial. N Engl J Med. PMID 37366315
  4. Bellido V, le Roux CW et al. (2026). Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial. Lancet. PMID 42810372
  5. Piatkowski T, Craven A et al. (2026). Composition and Labelling Accuracy of Products Sold as Retatrutide in Australia. Drug Alcohol Rev. PMID 42559975
  6. Branine N (2026). Online-Sourced Retatrutide Complicating Impending Diabetic Ketoacidosis in a Patient With Type 1 Diabetes and Concurrent Shigella Gastroenteritis. Cureus. PMID 42669023
  7. Panou T, Gouveri E et al. (2026). Retatrutide in type 2 diabetes mellitus and obesity: an overview. Expert Rev Clin Pharmacol. PMID 41785010

For laboratory research use only; not for human or animal consumption. This listing identifies the material, its documentation and the compound’s published literature, and makes no claim of efficacy or safety.

Additional information

Amount

10mg, 20mg

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