GLP-3 (RT) 5MG

110 in stock

Metabolic Research Peptides

GLP-3 (RT) 5MG

22 reviews

$72.99

GLP-3 (RT) 5mg — retatrutide (LY3437943), lyophilized research peptide in a sealed vial, for laboratory research only. A 39-residue synthetic triple agonist of the GIP, GLP-1 and glucagon receptors; investigational, not approved anywhere. No batch COA is posted yet for this strength — see the COA library. Priced in CAD, shipped within Canada by Canada Post. Not for human or animal use.

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Customer Reviews

4.86 out of 5
Based on 22 reviews
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  1. Darren Lee (verified owner) –

    ordered Retatrutide 5mg and the whole thing was pretty smooth. shipping updates were clear, no guessing game. clean experience.

  2. Molly Campbell (verified owner) –

    the Retatrutide 5mg listing answered most of my questions. support answered a small question before I ordered. would order again.

  3. Logan Hayes (verified owner) –

    size options was clear. I could see the size, price, and docs without clicking around forever.

  4. Taylor Taylor (verified owner) –

    not much to complain about with Retatrutide 5mg. the batch documentation was easier to read than most sites. worked out well.

  5. Sean King (verified owner) –

    the size options helped a lot. I always check COA info and labeling before I buy.

  6. Tina Brooks (verified owner) –

    placed a small order for Retatrutide 5mg and had no drama. the page felt clean, especially the COA section. pretty straightforward.

  7. Laura Ellis (verified owner) –

    came back for Retatrutide 5mg because the product page was clear. everything was packed tight and looked professional. thats all I needed.

  8. Kyle Ward (verified owner) –

    no weird checkout issues. Retatrutide 5mg showed up as listed.

  9. Nick Smith (verified owner) –

    Retatrutide 5mg was easy to find on the site. cart showed the right item and the right size. thats all I needed.

  10. Kara Anderson (verified owner) –

    fast ship, clean box, and the COA was easy to find for Retatrutide 5mg.

  11. Vanessa Cox (verified owner) –

    first time ordering Retatrutide 5mg from this shop. the page felt clean, especially the COA section. pretty straightforward.

  12. Maddie Miller (verified owner) –

    ordered Retatrutide 5mg and the whole thing was pretty smooth. COA info was easy to spot before checkout. nice and simple.

  13. Jordan Bailey (verified owner) –

    placed a small order for Retatrutide 5mg and had no drama. everything was packed tight and looked professional. good enough for a reorder.

  14. Joel Wood (verified owner) –

    I liked the docs layout on Retatrutide 5mg. shipping was normal and clean.

  15. Dustin Butler (verified owner) –

    simple order. Retatrutide 5mg page had the info I needed.

  16. Jared White (verified owner) –

    placed a small order for Retatrutide 5mg and had no drama. I liked that the research-only language stayed visible. thats all I needed.

  17. Oscar Cole (verified owner) –

    Retatrutide 5mg was easy to find on the site. the checkout email and tracking lined up fine. site feels much easier than a lot of peptide shops.

  18. Brianna Cole (verified owner) –

    came back for Retatrutide 5mg because the product page was clear. the bottle image and size info made it easy to double check. nice and simple.

  19. Megan Hughes (verified owner) –

    ordered Retatrutide 5mg and the whole thing was pretty smooth. support answered a small question before I ordered. site feels much easier than a lot of peptide shops.

  20. Logan Price (verified owner) –

    got Retatrutide 5mg without any back and forth. pretty smooth.

  21. Lauren Barnes (verified owner) –

    mobile checkout worked fine for Retatrutide 5mg. that matters to me.

  22. Ashley Ellis (verified owner) –

    not fancy, just clear. Retatrutide 5mg arrived packed well.

Description

GLP-3 (RT) 5mg — retatrutide research peptide, Canada

Researched & reviewed by the SPO Quality Team · Last reviewed: 30 September 2026

“GLP-3” is a catalogue label, not a hormone: the material in this vial is retatrutide (LY3437943), a single 39-residue peptide that Eli Lilly engineered to switch on the GIP, GLP-1 and glucagon receptors at once[1]. It is an investigational drug in late-stage trials and has no approval in any country[6]. The 5mg vial is the smallest strength of retatrutide on this site — lyophilized research-grade material for laboratory work only, not the trial drug.

Full research overview, study table & references → GLP-3 (retatrutide) in Canada: research guide

Identity at a glance

Compound Retatrutide (INN); LY3437943; catalogue name “GLP-3 (RT)”
Structure 39-residue single-chain peptide with a C20 fatty-diacid side chain at Lys17 and Aib at positions 2 and 20; C-terminal amide (FDA GSRS)
Formula / MW C221H342N46O68 / 4731 g/mol (PubChem CID 171390338)
CAS 2381089-83-2
Receptors studied GIP, GLP-1 and glucagon receptors — one molecule, three targets[1]
Status Investigational (Eli Lilly); not approved anywhere[6]

Batch documentation

A batch-specific COA for this strength has not been posted yet — see the COA library (/coa/). The Janoshik report in the library was run on a 10 mg vial batch and says nothing about this 5 mg lot; it is not reproduced here. When a report for a 5 mg batch is issued it will be embedded on this page.

What researchers have looked at

  • Design and receptor balance (2022): in vitro the molecule shows balanced glucagon- and GLP-1-receptor activity with stronger GIP-receptor activity; in obese mice, weight fell and glycaemic control improved, with the glucagon-receptor component adding energy expenditure[1].
  • Structure (2024): a structural study of how one peptide engages GLP-1R, GIPR and GCGR — the basis for the “triple agonist” description[2].
  • Phase 1b (2022, 72 adults with type 2 diabetes, 12 weeks): safety and tolerability were the primary outcome; gastrointestinal disorders were the most frequent adverse events, and 29 participants left the study early[3].
  • Gastric emptying (2023): a clinical pharmacology study reported that retatrutide delays gastric emptying[4].
  • Products sold online (2026): an Australian analysis examined the composition and labelling accuracy of products sold as “retatrutide”[5] — one reason a lot-specific report matters more than a product name.

These are findings about Lilly’s investigational compound in the models and trials named. They are not properties of this vial, and no benefit is claimed for the material sold here.

Storage and handling

  • Sealed vial at −20 °C for long-term storage (the site states up to 24 months as lyophilized powder); cool, dry and dark for short holds; avoid freeze–thaw cycling.
  • Lipidated peptides can aggregate in solution — make up only what an experiment needs. Reconstitution and handling protocols belong to the researcher and are not described on this site.

Other retatrutide listings: GLP-3 (RT) 10MG (posted COA) · GLP-3 (RT) 20MG · GLP-3 60MG · GLP-3 pen. Orders ship from inside Canada by Canada Post; the shipping policy has dispatch cut-off, delivery times and the free-shipping threshold. The full range is on the page where you can buy peptides online in Canada.

Frequently asked questions

Can I buy GLP-3 (RT) 5mg in Canada?

Yes. Shop Peptides Online supplies the 5mg vial of retatrutide (catalogue name GLP-3 (RT)) as research-grade lyophilized peptide and ships it from inside Canada by Canada Post. It is sold for laboratory research only; retatrutide is an investigational drug with no approval anywhere (PMID 41785010).

Is GLP-3 the same as retatrutide?

Yes — GLP-3 (RT) is this shop’s catalogue name for retatrutide, LY3437943. There is no natural hormone called GLP-3. The molecule is a synthetic 39-residue peptide designed to act on the GIP, GLP-1 and glucagon receptors together (PMID 35985340).

Is there a COA for GLP-3 (RT) 5mg?

Not yet for this strength. The report in the COA library belongs to a 10 mg vial batch and is not evidence for the 5 mg lot. When a 5 mg batch report is issued it will be embedded on this page.

Is GLP-3 (RT) for human use?

No. This vial is research-grade material for laboratory use only, not for human or animal consumption. Retatrutide is not approved by Health Canada, the FDA or the EMA; published trials are of Lilly’s investigational drug, not of this product; and Shop Peptides Online provides no dosing or administration guidance.

References

  1. Coskun T, Urva S et al. (2022). LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept. Cell Metab. PMID 35985340
  2. Li W, Zhou Q et al. (2024). Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide. Cell Discov. PMID 39019866
  3. Urva S, Coskun T et al. (2022). LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial. Lancet. PMID 36354040
  4. Urva S, O'Farrell L et al. (2023). The novel GIP, GLP-1 and glucagon receptor agonist retatrutide delays gastric emptying. Diabetes Obes Metab. PMID 37311727
  5. Piatkowski T, Craven A et al. (2026). Composition and Labelling Accuracy of Products Sold as Retatrutide in Australia. Drug Alcohol Rev. PMID 42559975
  6. Panou T, Gouveri E et al. (2026). Retatrutide in type 2 diabetes mellitus and obesity: an overview. Expert Rev Clin Pharmacol. PMID 41785010

For laboratory research use only. Not for human or animal consumption. This description identifies the material and summarises published literature on the compound; it makes no claim of efficacy or safety for the material sold.

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