NAD+ (Pen)

Description

NAD+ research pen — Canada

Researched & reviewed by the SPO Quality Team · Last reviewed: 30 September 2026

This listing is NAD+ in pen format (1000mg fill) — the same research material as our NAD+ vials, supplied in a pre-formatted research pen for laboratories that prefer logged, repeatable handling over loose vials. NAD+ (nicotinamide adenine dinucleotide) is the coenzyme that shuttles electrons in cellular metabolism and is used up by NAD-consuming enzymes such as sirtuins, PARP-1 and CD38^[1]. It is a dinucleotide, not a peptide. Laboratory research only; the pen is a handling format, not an instruction.

Full research overview, study table & references → NAD+ in Canada: research guide

Identity at a glance

Batch documentation: a batch-specific COA for the NAD+ pen has not been posted yet — see the COA library. Reports for the vial listings, where posted, are on those pages.

What researchers have looked at

• Supply and demand in muscle (2022 review): under normal conditions the NAMPT salvage pathway replaces what enzymes consume, but ageing and muscle contraction increase NAD+ use^[1].
• CD38 in ageing mice (2016): the NADase CD38 became more abundant and active with age and was needed for the age-linked fall in NAD, acting partly through SIRT3^[2].
• Added NAD+ in cell culture (2021): when HeLa cells were flooded with extracellular NAD+, a SIRT1-driven response brought internal levels back down by reducing uptake of its breakdown products^[3].
• Human skin (2012): in 49 tissue samples, NAD+ content fell with donor age while PARP activity rose, most clearly in males^[4].

These are cell, mouse and tissue findings. For people, a 2026 systematic review judged the clinical effect of raising NAD+ inconclusive^[5]; nothing here is a claim of benefit.

Storage and handling

• Follow the label: keep the pen cool, dry and out of light, and do not subject it to repeated freeze–thaw.
• Log the batch number and dates of receipt and first use, as with any research material. No protocol or administration information is provided here.

Vial strength: NAD+ 1000MG. Other pens are on the peptide pens page; the whole range is on our buy peptides online in Canada page. Canada Post from inside Canada (shipping policy).

Related reading: NAD+ vs NMN vs NR: the NAD+ precursors in research

Frequently asked questions

What is the NAD+ pen?

The same synthetic NAD+ supplied in a pre-formatted research pen rather than a loose vial, for laboratories that want repeatable, logged handling. It is a research format only; no administration guidance of any kind is given.

Is there a batch report for the NAD+ pen?

Not yet. No batch-specific report for the pen is posted in the COA library. The page will state the report when one exists.

Is the NAD+ pen for human use?

No. The pen is supplied for laboratory research only and is not for human or animal use. No dosing, administration or protocol information is provided.

Cited

1. Ji et al. (2022), Cells — PMID 35203360
2. Camacho-Pereira et al. (2016), Cell metabolism — PMID 27304511
3. Buonvicino et al. (2021), The Journal of biological chemistry — PMID 34097876
4. Massudi et al. (2012), PloS one — PMID 22848760
5. Gallagher et al. (2026), Ageing research reviews — PMID 41655607

For laboratory research use only. Not for human or animal consumption. No dosing, administration or protocol information is provided, and nothing here is a claim of efficacy or safety in humans.