Description
NAD+ 1000mg research compound — Canada
NAD+ (nicotinamide adenine dinucleotide) is the coenzyme that shuttles electrons in cellular metabolism and is used up by NAD-consuming enzymes such as sirtuins, PARP-1 and CD38[1]. It is a dinucleotide, not a peptide. This listing is a single sealed vial of lyophilized research-grade NAD+ at a 1000 mg labelled amount, for laboratory research only.
Full research overview, study table & references → NAD+ in Canada: research guide
Identity at a glance
| Name | NAD+ (nadide; β-NAD; coenzyme I) |
| Formula / MW | C21H27N7O14P2 · 663.4 g/mol |
| CAS | 53-84-9 |
| PubChem CID | 5892 |
| ChEMBL | CHEMBL1234613 |
| Declared content | 1000 mg per vial (label value; no measured value on file) |
Batch documentation: A batch-specific COA for this strength has not been posted yet — see the COA library (/coa/).
What researchers have looked at
- Supply and demand in muscle (2022 review): under normal conditions the NAMPT salvage pathway replaces what enzymes consume, but ageing and muscle contraction increase NAD+ use[1].
- CD38 in ageing mice (2016): the NADase CD38 became more abundant and active with age and was needed for the age-linked fall in NAD, acting partly through SIRT3[2].
- Added NAD+ in cell culture (2021): when HeLa cells were flooded with extracellular NAD+, a SIRT1-driven response brought internal levels back down by reducing uptake of its breakdown products[3].
- Human skin (2012): in 49 tissue samples, NAD+ content fell with donor age while PARP activity rose, most clearly in males[4].
These are cell, mouse and tissue findings. For people, a 2026 systematic review judged the clinical effect of raising NAD+ inconclusive[5]; nothing here is a claim of benefit.
Storage and handling
- Keep the sealed vial at −20 °C for long-term storage, dry and away from light; limit freeze–thaw cycles.
- Bacteriostatic water is listed separately. How the powder is dissolved and used is decided by the researcher.
Ships by Canada Post from inside Canada (shipping policy). Our peptides and related research compounds are gathered on the buy peptides online in Canada page.
Frequently asked questions
Can I buy NAD+ 1000mg in Canada?
Yes. The 1000mg vial ships from inside Canada by Canada Post, so there is no customs hold. It is research-grade material for laboratory use only.
Is a certificate of analysis posted for NAD+ 1000mg?
Not at the time of writing. A batch-specific COA for this strength has not been posted in the COA library, and no other product’s report is shown in its place. The page will be updated when one is posted.
Is NAD+ the same as NMN or nicotinamide riboside?
No. NMN and nicotinamide riboside are smaller NAD+ intermediates or precursors (PMID 21982712); this vial contains NAD+ itself, the finished dinucleotide. Much of the published animal work used the precursors rather than NAD+.
Is NAD+ 1000mg intended for human use?
No. It is sold for laboratory research only. Human studies of NAD+ itself are scarce, and a 2026 systematic review found no eligible outcome trials of injected NAD+ (PMID 41655607). No dosing or administration guidance is given.
Cited
- Ji et al. (2022), Cells — PMID 35203360
- Camacho-Pereira et al. (2016), Cell metabolism — PMID 27304511
- Buonvicino et al. (2021), The Journal of biological chemistry — PMID 34097876
- Massudi et al. (2012), PloS one — PMID 22848760
- Gallagher et al. (2026), Ageing research reviews — PMID 41655607
For laboratory research use only. Not for human or animal consumption. No dosing, administration or protocol information is provided, and nothing here is a claim of efficacy or safety in humans.
