Description
Tesamorelin 5mg research peptide — Canada
Researched & reviewed by the SPO Quality Team · Last reviewed: 30 September 2026
Tesamorelin (TH9507) is human growth-hormone-releasing factor, GHRH(1-44)-NH2, with a trans-3-hexenoyl group added to its first tyrosine[1]. This listing is the smallest vial in our tesamorelin range: one sealed vial of lyophilized research-grade tesamorelin at a 5 mg labelled amount, for laboratory research only.
Full research overview, study table & references → Tesamorelin in Canada: research guide
Identity at a glance
| Name |
Tesamorelin (TH9507) |
| Structure |
trans-3-hexenoyl-GHRH(1-44)-NH2 (44 aa) |
| Formula / MW |
C221H366N72O67S · 5136 g/mol |
| CAS / UNII |
218949-48-5 / MQG94M5EEO |
| PubChem CID |
16137828 |
| Declared content |
5 mg per vial (label value; no measured value on file) |
Batch documentation: A batch-specific COA for this strength has not been posted yet — see the COA library (/coa/).
What researchers have looked at
- Stability by design (2007): the N-terminal modification protected the peptide from DPP-IV and extended its plasma elimination in animal studies; rats and dogs tolerated repeated treatment, with more pronounced, reversible findings in dogs[1].
- Development history (2009 review): GHRH analogues were pursued as possibly better-tolerated alternatives to recombinant growth hormone, and tesamorelin was developed for conditions linked to relative GH deficiency, including HIV-related lipodystrophy[2].
- Beyond HIV (2012): a randomised, placebo-controlled trial in 152 older adults, 66 of them with mild cognitive impairment, examined cognitive test performance[4].
- Liver tissue (2020): paired biopsies from a randomised HIV-associated fatty-liver trial were analysed for hepatic gene-set changes with tesamorelin versus placebo[5].
Anti-doping note: GHRH and its synthetic analogues are prohibited by the World Anti-Doping Agency, and laboratories have developed in-vitro metabolite standards to detect tesamorelin in urine[6]. Trial designs above are listed to show where tesamorelin has been studied; they are not claims for this research material.
Storage and handling
- Freeze the sealed vial at −20 °C for long-term storage (site guidance: up to 24 months as dry powder); keep it dry and dark and avoid repeated freeze–thaw.
- Bacteriostatic water is sold separately; preparation is at the researcher’s discretion.
Other formats: TESAMORELIN 10MG · TESAMORELIN 20MG · Tesamorelin (Pen). Dispatched by Canada Post within Canada (shipping policy); the full catalogue is on our buy peptides online in Canada page.
Frequently asked questions
Can I buy tesamorelin 5mg in Canada?
Yes. The 5mg vial is shipped by Canada Post from within Canada, so there is no customs clearance. It is research-grade material for laboratory use only.
Is there a COA for the 5mg vial?
Not yet. A batch-specific COA for this strength has not been posted in the COA library. The reports posted for the 10mg and 20mg vials belong to those strengths and are not used for this one.
Is this the same as Egrifta?
No. Egrifta is the licensed medicine that the US FDA approved in 2010 for HIV-related lipodystrophy (PMID 21115997). In Health Canada’s Drug Product Database its Canadian listings are now cancelled. This vial is unlicensed research material.
Why is tesamorelin modified at the N-terminus?
The trans-3-hexenoyl group on tyrosine 1 made the peptide resistant to dipeptidyl aminopeptidase-IV and slowed its breakdown in rat, dog and human plasma compared with natural GHRH(1-44) (PMID 17214611).
Cited
- Ferdinandi et al. (2007), Basic & clinical pharmacology & toxicology — PMID 17214611
- Wang et al. (2009), Expert opinion on investigational drugs — PMID 19243281
- Traynor (2010), American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists — PMID 21115997
- Baker et al. (2012), Archives of neurology — PMID 22869065
- Fourman et al. (2020), JCI insight — PMID 32701508
- Memdouh et al. (2021), Drug testing and analysis — PMID 34665524
For laboratory research use only. Not for human or animal consumption. No dosing, administration or protocol information is provided, and nothing here is a claim of efficacy or safety in humans.
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