MOTS-C 20MG

34 in stock

Skin & Cellular Research Peptides

MOTS-C 20MG

18 reviews

$108.99

MOTS-c 20mg research peptide, vial format, supplied for laboratory research only. MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial genome (a mitochondrial-derived peptide). Independent batch documentation in the COA library; priced in CAD and shipped within Canada by Canada Post. Not for human or animal use.

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Customer Reviews

4.89 out of 5
Based on 18 reviews
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  1. Kevin Ward (verified owner) –

    MOTS-C 20mg was easy to find on the site. the bottle image and size info made it easy to double check. site feels much easier than a lot of peptide shops.

  2. Olivia Stewart (verified owner) –

    got MOTS-C 20mg in my cart without having to hunt around. price and size were clear on mobile. thats all I needed.

  3. Courtney Anderson (verified owner) –

    got MOTS-C 20mg without any back and forth. pretty smooth.

  4. Jeremy Walker (verified owner) –

    grabbed MOTS-C 20mg after comparing a few listings. the product card made it easy to compare sizes. better than expected.

  5. Diana Jenkins (verified owner) –

    placed a small order for MOTS-C 20mg and had no drama. the checkout email and tracking lined up fine. site feels much easier than a lot of peptide shops.

  6. Karen Brooks (verified owner) –

    pretty easy order. MOTS page matched what showed in the cart.

  7. Leah Jenkins (verified owner) –

    came back for MOTS-C 20mg because the product page was clear. the label matched the item I picked, which I always check first. better than expected.

  8. Aaron Edwards (verified owner) –

    solid experience buying MOTS-C 20mg. received exactly what was on the order page. nice and simple.

  9. Anthony Diaz (verified owner) –

    got MOTS-C 20mg in my cart without having to hunt around. the batch documentation was easier to read than most sites. worked out well.

  10. Tyler Foster (verified owner) –

    good packaging on MOTS-C 20mg. label and size matched the order.

  11. Nicole Mitchell (verified owner) –

    happy with the way MOTS-C 20mg was packaged. no loose bottle.

  12. Oscar Hayes (verified owner) –

    grabbed MOTS-C 20mg after comparing a few listings. the product card made it easy to compare sizes. thats all I needed.

  13. Patrick Foster (verified owner) –

    ordered MOTS-C 20mg and the whole thing was pretty smooth. delivery was faster than I expected for a first order. clean experience.

  14. Sam Thompson (verified owner) –

    mobile checkout worked fine for MOTS-C 20mg. that matters to me.

  15. Courtney Wilson (verified owner) –

    came back for MOTS-C 20mg because the product page was clear. COA info was easy to spot before checkout. good enough for a reorder.

  16. Nicole Rivera (verified owner) –

    placed a small order for MOTS-C 20mg and had no drama. the checkout email and tracking lined up fine. better than expected.

  17. Anthony Diaz (verified owner) –

    i liked how MOTS-C 20mg was laid out on the page. the batch documentation was easier to read than most sites. worked out well.

  18. Ashley Long (verified owner) –

    MOTS-C 20mg came in fine. checkout was quick and tracking was easy to follow.

Description

MOTS-c 20mg research peptide — Canada

Researched & reviewed by the SPO Quality Team · Last reviewed: 30 September 2026

Our mid-range MOTS-c vial. The peptide is a sixteen-residue product of the mitochondrial 12S rRNA gene, studied since 2015 as a regulator of muscle metabolism in mice[1]; more recent mouse work has looked at muscle wasting, myostatin and a naturally occurring inactive variant[2, 3, 4]. Lyophilized synthetic peptide in a sealed vial, supplied for laboratory research only.

Full research overview, study table & references → MOTS-c in Canada: research guide

Identity at a glance

Name MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c)
Sequence MRWQEMGYIFYPRKLR (16 aa)
Formula / MW C101H152N28O22S2 · 2174.6 g/mol
CAS / UNII 1627580-64-6 / A5CV6JFB78
PubChem CID 146675088
Declared content 20 mg per vial (label value; no measured value on file)

Batch documentation: a batch-specific COA for this strength has not been posted yet — see the COA library.

What researchers have looked at

  • Muscle atrophy signalling (2021): in C2C12 myotubes MOTS-c prevented palmitate-induced atrophy through a CK2–PTEN–mTORC2–AKT–FOXO1 route, and in diet-induced obese mice it lowered plasma myostatin; in people, plasma MOTS-c and myostatin were inversely correlated[2].
  • Immobilised mice (2024): eight days in a cast cost control mice about 15% of muscle mass versus about 5% with MOTS-c, with lower IL-6, IL-1β, CXCL1 and MCP-1 and less fat inside the muscle[3].
  • A less active natural variant (2021): the K14Q form failed to lower weight or improve glucose tolerance in high-fat-fed male mice where the wild-type peptide did; female mice were unaffected by either[4].
  • Limits: the original metabolic findings are mouse data[1], and a 2022 review of MOTS-c in ageing notes the absence of clinical application[5]. Nothing here is a claim about people.

Storage and handling

  • Long-term at −20 °C as sealed lyophilized powder (the site gives up to 24 months); cool, dry and dark short-term; avoid freeze–thaw cycling.
  • Dissolves in water; the 2024 mouse study used sterilised water as its vehicle[3]. Bacteriostatic water is stocked separately.

Other strengths: MOTS-C 10MG · MOTS-C 40MG · MOTS-C (Pen). Canada Post from inside Canada; cut-offs and the free-shipping threshold are in the shipping policy, and you can buy peptides online in Canada across the whole catalogue.

Frequently asked questions

Can I buy MOTS-c 20mg in Canada?

Yes — shipped by Canada Post from inside Canada, so no customs clearance. Laboratory research only; there is no approved MOTS-c product anywhere.

Does the 20mg vial have a batch report?

No report for the 20 mg strength is posted in the COA library yet. We do not reuse another strength’s document; this page will state the report when one is posted.

What is the K14Q variant mentioned in the research?

An East-Asian mitochondrial DNA polymorphism (m.1382A>C) that changes the 14th residue of MOTS-c from lysine to glutamine. In three cohorts totalling 27,527 people, men carrying it had a higher prevalence of type 2 diabetes, and the variant peptide was less active in mice and cells (PMID 33468709).

Is MOTS-c approved or used in people?

No. Synthetic MOTS-c has not been given to people in any published trial, and reviews describe it as a research peptide without a developed clinical use (PMID 36233287). This listing is for laboratory research; no dosing or administration guidance is provided.

Cited

  1. Lee et al. (2015), Cell metabolism — PMID 25738459
  2. Kumagai et al. (2021), American journal of physiology. Endocrinology and metabolism — PMID 33554779
  3. Kumagai et al. (2024), American journal of physiology. Endocrinology and metabolism — PMID 38170165
  4. Zempo et al. (2021), Aging — PMID 33468709
  5. Mohtashami et al. (2022), International journal of molecular sciences — PMID 36233287

For laboratory research use only. Not for human or animal consumption. No dosing, administration or protocol information is provided, and nothing here is a claim of efficacy or safety in humans.

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