Customer Reviews

4.83 out of 5
Based on 30 reviews
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  1. Chelsea Cooper (verified owner) –

    i liked how MOTS-C 10mg was laid out on the page. checkout didnt fight me and the summary looked right. thats all I needed.

  2. Travis Richardson (verified owner) –

    solid experience buying MOTS-C 10mg. the product card made it easy to compare sizes. nice and simple.

  3. Karen Carter (verified owner) –

    grabbed MOTS-C 10mg after comparing a few listings. received exactly what was on the order page. worked out well.

  4. Jessica Wood (verified owner) –

    first time ordering MOTS-C 10mg from this shop. the checkout email and tracking lined up fine. nice and simple.

  5. Amanda Ellis (verified owner) –

    solid experience buying MOTS-C 10mg. packaging was neat and nothing was leaking or loose. nice and simple.

  6. Katelyn Brooks (verified owner) –

    got MOTS-C 10mg in my cart without having to hunt around. packaging was neat and nothing was leaking or loose. pretty straightforward.

  7. Joel Brown (verified owner) –

    ordered MOTS-C 10mg and the whole thing was pretty smooth. I liked that the research-only language stayed visible. nice and simple.

  8. Jenna Fisher (verified owner) –

    good packaging on MOTS-C 10mg. label and size matched the order.

  9. Jessica Scott (verified owner) –

    the site made it easy to review MOTS-C 10mg before ordering.

  10. Carter Ross (verified owner) –

    ordered MOTS-C 10mg and the whole thing was pretty smooth. COA info was easy to spot before checkout. would order again.

  11. Nick Gray (verified owner) –

    got MOTS-C 10mg in my cart without having to hunt around. support answered a small question before I ordered. no issues from my side.

  12. Jake Walker (verified owner) –

    fast ship, clean box, and the COA was easy to find for MOTS-C 10mg.

  13. Aaron King (verified owner) –

    MOTS-C 10mg was easy to find on the site. the checkout email and tracking lined up fine. clean experience.

  14. Logan Davis (verified owner) –

    got MOTS-C 10mg in my cart without having to hunt around. the label matched the item I picked, which I always check first. no issues from my side.

  15. Kara Bennett (verified owner) –

    got MOTS-C 10mg without any back and forth. pretty smooth.

  16. Oscar Fisher (verified owner) –

    product card was clear. I could see the size, price, and docs without clicking around forever.

  17. Shane Gonzales (verified owner) –

    the MOTS-C listing helped a lot. I always check COA info & labeling before I buy.

  18. Justin Butler (verified owner) –

    I liked the docs layout on MOTS-C 10mg. shipping was normal and clean.

  19. Cameron Cooper (verified owner) –

    the MOTS-C 10mg listing answered most of my questions. the product card made it easy to compare sizes. site feels much easier than a lot of peptide shops.

  20. Alicia Gonzales (verified owner) –

    MOTS-C 10mg was easy to find on the site. COA info was easy to spot before checkout. site feels much easier than a lot of peptide shops.

  21. Jordan Smith (verified owner) –

    grabbed MOTS-C 10mg after comparing a few listings. the product card made it easy to compare sizes. clean experience.

  22. Anthony Roberts (verified owner) –

    liked the MOTS-C listing. package l&ed in good shape and the email updates were on time.

  23. Cameron Lee (verified owner) –

    the MOTS page made it easy to verify what I was ordering. no surprises at checkout.

  24. Alicia Reed (verified owner) –

    ordered MOTS-C 10mg and the whole thing was pretty smooth. the batch documentation was easier to read than most sites. thats all I needed.

  25. Lucas Lewis (verified owner) –

    got MOTS-C 10mg in my cart without having to hunt around. the page felt clean, especially the COA section. no issues from my side.

  26. Justin Watson (verified owner) –

    quick order for MOTS-C 10mg, simple checkout. price and size were clear on mobile. overall happy with it.

  27. Carter Wood (verified owner) –

    no weird checkout issues. MOTS-C 10mg showed up as listed.

  28. Casey James (verified owner) –

    not much to complain about with MOTS-C 10mg. the checkout email and tracking lined up fine. worked out well.

  29. Ethan Thomas (verified owner) –

    the MOTS-C 10mg listing answered most of my questions. the bottle image and size info made it easy to double check. pretty straightforward.

  30. Jenna Thompson (verified owner) –

    ordered MOTS-C 10mg and the whole thing was pretty smooth. shipping updates were clear, no guessing game. good enough for a reorder.

Description

MOTS-c 10mg research peptide — Canada

MOTS-c is the peptide that showed the mitochondrial genome can encode signals of its own: sixteen residues (MRWQEMGYIFYPRKLR) read from a short open reading frame inside the 12S ribosomal RNA gene, first described in 2015[1]. The 10mg vial is the entry strength in our range. Synthetic lyophilized powder, one sealed vial, laboratory research only.

Full research overview, study table & references → MOTS-c in Canada: research guide

Identity at a glance

Name MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c)
Sequence MRWQEMGYIFYPRKLR (16 aa)
Formula / MW C101H152N28O22S2 · 2174.6 g/mol
CAS / UNII 1627580-64-6 / A5CV6JFB78
PubChem CID 146675088
Declared content 10 mg per vial (label value; no measured value on file)

Batch documentation: a batch-specific COA for this strength has not been posted yet — see the COA library.

What researchers have looked at

  • Metabolism in mice (2015): the discovery study found that MOTS-c inhibits the folate cycle and de-novo purine synthesis, activating AMPK, and that treated mice were protected from age-dependent and diet-induced insulin resistance and from diet-induced obesity[1].
  • Nuclear signalling (2018): under glucose restriction the peptide moved into the nucleus in an AMPK-dependent way and regulated antioxidant-response genes with NRF2[2].
  • Ageing mice and exercise (2021): MOTS-c enhanced physical performance in 2-, 12- and 22-month-old mice, and in humans exercise raised endogenous MOTS-c in muscle and blood[3].
  • Limits: the human evidence is observational — for instance plasma MOTS-c in ten lean and ten obese adults[4] — and reviews state that no clinical application has been developed[5].

Storage and handling

  • Sealed vial at −20 °C for long-term storage (site guidance: up to 24 months as dry powder); cool, dry and dark for short periods; no repeated freeze–thaw.
  • Water-soluble; bacteriostatic water is listed separately. Protocols are the researcher’s own.

Other strengths: MOTS-C 20MG · MOTS-C 40MG · MOTS-C (Pen). Ships by Canada Post from inside Canada (shipping policy); the full range is on our buy peptides online in Canada page.

Frequently asked questions

Can I buy MOTS-c 10mg in Canada?

Yes. This vial ships from inside Canada by Canada Post, with no customs hold. It is supplied for laboratory research only; MOTS-c has no approved product anywhere.

Is a COA posted for the MOTS-c 10mg vial?

Not at the time of writing. No batch report for any MOTS-c listing is in the COA library, and this page does not borrow another product’s document. It will be updated when a report is posted.

What was MOTS-c discovered to do in mice?

In the 2015 discovery paper, MOTS-c treatment prevented age-dependent and high-fat-diet-induced insulin resistance and diet-induced obesity in mice, acting on skeletal muscle through the folate cycle and AMPK (PMID 25738459). These are mouse findings, not claims about people.

Is MOTS-c for human use?

No. No published trial has given synthetic MOTS-c to people; human studies measured the body’s own peptide (PMID 29593067). Reviews note that no clinical method of using it has been developed (PMID 36761202). This vial is for laboratory research; no dosing or administration guidance is given.

Cited

  1. Lee et al. (2015), Cell metabolism — PMID 25738459
  2. Kim et al. (2018), Cell metabolism — PMID 29983246
  3. Reynolds et al. (2021), Nature communications — PMID 33473109
  4. Cataldo et al. (2018), Journal of investigative medicine : the official publication of the American Federation for Clinical Research — PMID 29593067
  5. Zheng et al. (2023), Frontiers in endocrinology — PMID 36761202

For laboratory research use only. Not for human or animal consumption. No dosing, administration or protocol information is provided, and nothing here is a claim of efficacy or safety in humans.

Additional information

Format

Vial, Pen